Aflatoxin B₁ (AFB₁), the most toxic and harmful mycotoxin, has a high likelihood of occurring in animal feed and human food, which seriously affects agriculture and food safety and endangers animal and human health. Recently, natural plant products have attracted widespread attention due to their low toxicity, high biocompatibility, and simple composition, indicating significant potential for resisting AFB₁. The mechanisms by which these phytochemicals resist toxins mainly involve antioxidative, anti-inflammatory, and antiapoptotic pathways. Moreover, these substances also inhibit the genotoxicity of AFB₁ by directly influencing its metabolism in vivo, which contributes to its elimination. Here, we review various phytochemicals that resist AFB₁ and their anti-AFB₁ mechanisms in different animals, as well as the common characteristics of phytochemicals with anti-AFB₁ function. Additionally, the shortcomings of current research and future research directions will be discussed. Overall, this comprehensive summary contributes to the better application of phytochemicals in agriculture and food safety.

中文翻译：

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农业和食品科学中植物化学物质对黄曲霉毒素 B1 的解毒


黄曲霉毒素B ₁ （AFB ₁ ）是毒性最强、危害最大的霉菌毒素，极有可能出现在动物饲料和人类食品中，严重影响农业和食品安全，危害动物健康。和人类健康。近年来，天然植物产品因其低毒、生物相容性高、成分简单而受到广泛关注，显示出抗AFB ₁ 的巨大潜力。这些植物化学物质抵抗毒素的机制主要涉及抗氧化、抗炎和抗凋亡途径。此外，这些物质还通过直接影响AFB ₁ 在体内的代谢来抑制其遗传毒性，从而有助于其消除。在此，我们综述了各种抗AFB ₁ 的植物化学物质及其在不同动物体内的抗AFB ₁ 机制，以及抗AFB ₁