In the rapidly moving field of stem cell and embryo research, research questions often sit at the intersection of scientific inquiry and ethical considerations. The International Society for Stem Cell Research (ISSCR) produces guidelines to help navigate decisions in this area. For Cell’s 50th Anniversary Focus on Developmental Biology, scientific editor Sarah Geisler discussed the importance of the ISSCR guidelines on stem cell and embryo research for both the stem cell community and the broader public with Amander Clark, Robin Lovell-Badge, and Janet Rossant, who have been involved in the ongoing evolution of the guidelines. A lightly edited transcript of their conversation is shared here.

在快速发展的干细胞和胚胎研究领域，研究问题常常处于科学探究和伦理考虑的交叉点。国际干细胞研究协会 (ISSCR) 制定了指导方针来帮助指导该领域的决策。在《Cell 》聚焦发育生物学 50 周年之际，科学编辑 Sarah Geisler 与 Amander Clark、Robin Lovell-Badge 和 Janet Rossant 讨论了 ISSCR 干细胞和胚胎研究指南对干细胞界和广大公众的重要性，他们参与了指南的不断发展。此处分享了经过轻微编辑的谈话记录。