ObjectiveTo assess acute and long‐term stress in men and women after the detection of fetal anomalies leading to pregnancy termination.DesignProspective observational study.SettingTertiary referral centre for fetal medicine.PopulationFrom the initial sample of 180 pregnant women with a fetal anomaly detected by ultrasound examination, a total of 87 women terminated their pregnancy, with 72 partners included in the sample. At the time of detection, the group of women (n = 93) and their partners (n = 81) who did not terminate the pregnancy following a diagnosis were included as a comparison group.MethodsThese women and their partners were asked to complete the Edinburgh Postnatal Depression Scale (EPDS) and the Impact of Events Scale (IES) questionnaires, both at the time of initial detection and at 6 weeks after the termination of the pregnancy.Main outcome measuresResponses to the EPDS and the IES at the time of initial detection and at 6 weeks after pregnancy termination.ResultsWomen who underwent pregnancy termination reported higher symptom levels of depression, but not traumatic stress, prior to the termination than women who chose not to terminate their pregnancy. Among men, there was a difference across depression and all subscales of traumatic stress (e.g. IES intrusion: mean difference 5.31; 95% CI 2.32–8.31). Women experienced more depressive symptoms over time than men (β = 4.33, P < 0.001) and higher symptom levels on all subscales of traumatic stress (e.g. IES intrusion: β = 5.27; P < 0.001).ConclusionsOverall, our study underscores the heightened levels of depression and traumatic stress experienced by prospective parents, particularly prior to the decision to terminate a pregnancy following the detection of a fetal anomaly. Although women generally report more pronounced symptoms, it is noteworthy that men also experience considerable traumatic stress during this challenging time.

中文翻译：

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检测到胎儿异常后终止妊娠的男性和女性的抑郁和创伤应激的急性症状：一项前瞻性观察研究


目的评估男性和女性在检测到胎儿异常导致终止妊娠后的急性和长期压力。设计前瞻性观察研究。设置胎儿医学三级转诊中心。人群来自 180 名经超声检查发现胎儿异常的孕妇的初始样本共有 87 名妇女终止妊娠，样本中包括 72 名伴侣。检测时，这群女性（ n = 93) 和他们的合作伙伴 ( n = 81) 诊断后未终止妊娠的人被纳入对照组。 方法 这些妇女及其伴侣被要求填写爱丁堡产后抑郁量表 (EPDS) 和事件影响量表 (IES) 问卷，均在初次检测时和终止妊娠后 6 周。主要结局指标在初次检测时和终止妊娠后 6 周对 EPDS 和 IES 的反应。结果接受终止妊娠的女性报告抑郁症状水平较高，但在终止妊娠之前，与选择不终止妊娠的女性相比，创伤性应激没有影响。在男性中，抑郁症和创伤应激的所有子量表都存在差异（例如IES侵入：平均差5.31；95% CI 2.32-8.31）。随着时间的推移，女性比男性经历更多的抑郁症状（β = 4.33，磷< 0.001）以及创伤应激所有分量表上的更高症状水平（例如 IES 侵入：β = 5.27；磷< 0.001）。结论总体而言，我们的研究强调了准父母所经历的抑郁和创伤性应激水平升高，特别是在检测到胎儿异常后决定终止妊娠之前。尽管女性通常报告更明显的症状，但值得注意的是，男性在这个充满挑战的时期也经历了相当大的创伤压力。