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Channeling kynurenine
Nature Chemical Biology ( IF 12.9 ) Pub Date : 2024-06-19 , DOI: 10.1038/s41589-024-01643-z
Mollie I. Sweeney , David M. Tobin

An in vivo chemical screen has uncovered a potential role for a tryptophan metabolite in promoting host survival during bacterial infections through modulation of ionotropic glutamate receptors. Host-directed therapies for bacterial infections offer a largely untapped approach to treatment.

中文翻译:

 引导犬尿氨酸


体内化学筛选揭示了色氨酸代谢物通过调节离子型谷氨酸受体在细菌感染期间促进宿主存活的潜在作用。针对细菌感染的宿主导向疗法提供了一种很大程度上尚未开发的治疗方法。
更新日期:2024-06-19
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