With the benefit of hindsight, recognition of the cancer susceptibility gene BRCA1 and its later cloning were defining moments for breast and ovarian cancer genetics that should be celebrated. Thirty years after the discovery and cloning of the cancer susceptibility gene BRCA1, William Foulkes reflects on this defining moment for breast and ovarian cancer genetics and how far the field has come.

中文翻译：

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BRCA1 和朋友 30 周年


事后看来，对癌症易感基因 BRCA1 的认识及其后来的克隆是乳腺癌和卵巢癌遗传学的决定性时刻，值得庆祝。在发现并克隆癌症易感基因 BRCA1 三十年后，William Foulkes 回顾了乳腺癌和卵巢癌遗传学的这一决定性时刻以及该领域取得的进展。