Centenarians — who are a putative model of healthy longevity — often have a low risk of cardiovascular disease, despite an age-associated decline in kidney function. An understanding of the molecular and cellular underpinnings of health kidney ageing in centenarians may provide clues for the prevention or alleviation of the burden of kidney disease in older populations.

中文翻译：

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健康老龄化与肾脏——百岁老人的教训


百岁老人——被认为是健康长寿的典范——尽管肾功能随年龄增长而下降，但患心血管疾病的风险通常较低。了解百岁老人健康肾脏衰老的分子和细胞基础可能为预防或减轻老年人肾脏疾病负担提供线索。