The formation of carbon-fluorine (C-F) bonds is an important research field in organic synthesis because the insertion of a fluorine atom into an organic compound can alter its physicochemical properties, such as metabolic stability and permeability. Due to this unique property, organic fluorinated compounds, especially aryl fluorides, have a wide range of applications in various fields, including agrochemicals, pharmaceuticals, and materials science. Therefore, numerous metal- or metal-free-mediated fluorination reactions have been developed to synthesize aryl fluorides. In this mini-review, we summarize recent ten years’ advances in fluorination reactions for the synthesis of aryl fluorides.

中文翻译：

---

用于合成芳基氟化物的（放射）氟化反应：最新进展和前景


碳氟（C-F）键的形成是有机合成中的一个重要研究领域，因为将氟原子插入有机化合物中可以改变其物理化学性质，例如代谢稳定性和渗透性。由于这种独特的性质，有机氟化物，特别是芳基氟化物，在农用化学品、制药和材料科学等各个领域具有广泛的应用。因此，已经开发了许多金属或无金属介导的氟化反应来合成芳基氟化物。在这篇小综述中，我们总结了近十年来芳基氟化物合成的氟化反应的进展。