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Unlocking the promise of RAS inhibition in pancreatic cancer
Nature Reviews Gastroenterology & Hepatology ( IF 45.9 ) Pub Date : 2024-06-14 , DOI: 10.1038/s41575-024-00951-y
Saurav D. Haldar , Nilofer S. Azad

The advent of next-generation RAS inhibitors brings renewed optimism to the care of patients with pancreatic cancer after decades of failure for novel therapeutics. A recent study highlights the potent antitumour activity of the multi-selective RAS(ON) inhibitor RMC-7977 across a spectrum of preclinical pancreatic cancer models.

中文翻译:


释放 RAS 抑制在胰腺癌中的前景



在新疗法数十年失败后,下一代 RAS 抑制剂的出现为胰腺癌患者的治疗带来了新的乐观情绪。最近的一项研究强调了多选择性 RAS(ON) 抑制剂 RMC-7977 在一系列临床前胰腺癌模型中的有效抗肿瘤活性。
更新日期:2024-06-14
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