Bimetallic-metal organic frameworks (BiM-MOFs) or bimetallic organic frameworks represent an innovative and promising class of porous materials, distinguished from traditional monometallic MOFs by their incorporation of two metal ions alongside organic linkers. BiM-MOFs, with their unique crystal structure, physicochemical properties, and composition, demonstrate distinct advantages in the realm of biochemical sensing applications, displaying improvements in optical properties, stability, selectivity, and sensitivity. This comprehensive review explores into recent advancements in leveraging BiM-MOFs for fluorescence-based biochemical sensing, providing insights into their design, synthesis, and practical applications in both chemical and biological sensing. Emphasizing fluorescence emission as a transduction mechanism, the review aims to guide researchers in maximizing the potential of BiM-MOFs across a broader spectrum of investigations. Furthermore, it explores prospective research directions and addresses challenges, offering valuable perspectives on the evolving landscape of fluorescence-based probes rooted in BiM-MOFs.

中文翻译：

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双金属-金属有机框架的最新进展：制备、性能和基于荧光的生化传感应用


双金属-金属有机框架（BiM-MOF）或双金属有机框架代表了一类创新且有前途的多孔材料，与传统的单金属 MOF 的区别在于它们在有机连接体旁边结合了两种金属离子。 BiM-MOFs以其独特的晶体结构、物理化学性质和成分，在生化传感应用领域表现出明显的优势，在光学性质、稳定性、选择性和灵敏度方面表现出改进。这篇全面的综述探讨了利用 BiM-MOF 进行基于荧光的生化传感的最新进展，深入了解它们在化学和生物传感中的设计、合成和实际应用。该综述强调荧光发射作为一种转导机制，旨在指导研究人员在更广泛的研究中最大限度地发挥 BiM-MOF 的潜力。此外，它还探索了前瞻性研究方向并解决了挑战，为基于 BiM-MOF 的荧光探针的不断发展提供了宝贵的视角。