Kashin-Beck disease (KBD) is an endemic, degenerative, and cartilage-damaging disease for which low selenium and T-2 toxins are considered environmental pathogenic factors. This study aimed to investigate the molecular mechanisms of autophagy in cartilage damage caused by T-2 toxin and the protective effect of chondroitin sulfate A nano-elemental selenium (CSA-SeNP) on the cartilage.

中文翻译：

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T-2毒素通过AKT/TSC/Rheb/mTOR信号通路介导的软骨细胞自噬及CSA-SeNP的保护作用


大骨节病 (KBD) 是一种地方性、退行性、软骨损伤性疾病，低硒和 T-2 毒素被认为是环境致病因素。本研究旨在探讨T-2毒素引起的软骨损伤中自噬的分子机制以及硫酸软骨素A纳米元素硒（CSA-SeNP）对软骨的保护作用。