Synovial pathology has been linked to osteoarthritis (OA) pain in patients. Microscopic grading systems for synovial changes in human OA have been described, but a standardized approach for murine models of OA is needed. We sought to develop a reproducible approach and set of minimum recommendations for reporting of synovial histopathology in mouse models of OA.

中文翻译：

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评估和报告两种手术诱导的骨关节炎小鼠模型滑膜组织病理学的标准化方法


滑膜病理学与患者骨关节炎 (OA) 疼痛有关。人类 OA 滑膜变化的微观分级系统已经被描述，但需要一种针对 OA 小鼠模型的标准化方法。我们试图开发一种可重复的方法和一套最低限度的建议来报告 OA 小鼠模型的滑膜组织病理学。