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Estimating the Effect of Radical Prostatectomy: Combining Data From the SPCG4 and PIVOT Randomized Trials With Contemporary Cohorts.
The Journal of Urology ( IF 5.9 ) Pub Date : 2024-06-12 , DOI: 10.1097/ju.0000000000004039
Andrew Vickers 1 , Emily Vertosick 1 , Lisa Langsetmo 2, 3 , Philipp Dahm 2, 4 , Gunnar Steineck 5 , Timothy J Wilt 2, 3, 6
Affiliation  

Two randomized trials (SPCG4 and PIVOT) have compared surgery to conservative management for localized prostate cancer. The applicability of these trials to contemporary practice remains uncertain. We aimed to develop an individualized prediction model for prostate cancer mortality comparing immediate surgery at a high-volume center to active surveillance.

中文翻译:


估计根治性前列腺切除术的效果:将 SPCG4 和 PIVOT 随机试验的数据与当代队列相结合。



两项随机试验(SPCG4 和 PIVOT)对局限性前列腺癌的手术与保守治疗进行了比较。这些试验在当代实践中的适用性仍不确定。我们的目标是开发一种前列腺癌死亡率的个体化预测模型,将大容量中心的立即手术与主动监测进行比较。
更新日期:2024-06-12
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