In this issue of Cell Host & Microbe, Shang et al. identify murine neuropilin 1 as a host factor that binds reovirus particles, directing cell entry and contributing to viral dissemination and neurovirulence. This study highlights the reovirus model system to investigate host receptors and their significance in viral pathogenesis.

中文翻译：

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Neuropilin 邀请呼肠孤病毒进入神经元

在本期《细胞宿主与微生物》中，Shang 等人。确定鼠神经毡蛋白 1 是结合呼肠孤病毒颗粒的宿主因子，指导细胞进入并促进病毒传播和神经毒力。这项研究重点介绍了呼肠孤病毒模型系统，以研究宿主受体及其在病毒发病机制中的重要性。