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Colorectal cancer clocks in on TIME
Nature Immunology ( IF 27.7 ) Pub Date : 2024-06-12 , DOI: 10.1038/s41590-024-01874-1 Amelia M Knudsen-Clark 1 , Brian J Altman 2, 3
Nature Immunology ( IF 27.7 ) Pub Date : 2024-06-12 , DOI: 10.1038/s41590-024-01874-1 Amelia M Knudsen-Clark 1 , Brian J Altman 2, 3
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Immune responses are subject to circadian regulation, but circadian effects on antitumor immune response are unknown. Disruption of intestinal circadian rhythms is now shown to promote immunosuppression by altering the tumor immune microenvironment (TIME) in colorectal cancer.
中文翻译：
结直肠癌按时出现
免疫反应受昼夜节律调节，但昼夜节律对抗肿瘤免疫反应的影响尚不清楚。现在证明，肠道昼夜节律的破坏可以通过改变结直肠癌的肿瘤免疫微环境（TIME）来促进免疫抑制。
更新日期：2024-06-12
中文翻译：
结直肠癌按时出现
免疫反应受昼夜节律调节，但昼夜节律对抗肿瘤免疫反应的影响尚不清楚。现在证明，肠道昼夜节律的破坏可以通过改变结直肠癌的肿瘤免疫微环境（TIME）来促进免疫抑制。
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