Tacrolimus is a calcineurin inhibitor rarely associated with gastrointestinal injury and reported only a handful of times in the literature. We present a case report demonstrating late-onset colitis in a patient taking tacrolimus for years, with typical histological features, associated with delayed mucosal healing. We hope this highlights the potential variability in both presentation and resolution in cases of tacrolimus-induced colitis.

中文翻译：

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晚发他克莫司诱发的结肠炎与粘膜愈合延迟相关：病例报告


他克莫司是一种钙调神经磷酸酶抑制剂，很少与胃肠道损伤相关，文献中只报道过几次。我们提出了一份病例报告，证明一名服用他克莫司多年的患者出现迟发性结肠炎，具有典型的组织学特征，与粘膜愈合延迟相关。我们希望这突显了他克莫司诱发的结肠炎病例在表现和解决方面的潜在变异性。