Humic substances (HSs), as the “black gold” of global agriculture, have a crucial environmental significance in cleaning harmful compounds, maintaining carbon mass balance, and increasing crop productivity. Unfortunately, the resources of HSs extracted from nature are insufficient, causing the supply, demand, and budget of the humus market to gradually increase. Given the analogous architectures of lignin and HSs, artificially regulated humification (ARH) has a great potential for directionally controlling the oxidative cleavage of lignin and/or the radical copolymerization of lignin precursors, to produce reassembled oligomers and/or polymers that can compare favorably with the function and efficacy of HSs. Herein, different ARH strategies are innovatively proposed to tackle hazardous chemicals and create humic-like biostimulators (H-LBs). We briefly describe the characteristics and functionalities of natural HSs, and summarize the latest approaches and mechanisms of lignin and its precursor-based ARH. In particular, the ARH routes of bio-composting, laccase catalysis, white-rot fungal degradation, Fenton-based advanced oxidation, and hydrothermal humification are comparatively highlighted to govern harmful substrates, enhance carbon sequestration, generate H-LBs, and practice sustainable agriculture. Furthermore, the mechanisms for promoting crop growth of H-LBs are also illustrated. Advances in modulating humification pathways may solve the technological bottlenecks of ARH in-situ and ex-situ by well-stocked lignin and its small derivatives, which are important for decontaminating contaminants, reducing CO₂ emissions, and enriching H-LBs in agroecosystems.

腐殖质（HS）作为全球农业的“黑金”，在净化有害化合物、维持碳质量平衡和提高作物生产力方面具有至关重要的环境意义。不幸的是，从自然界提取的HS资源不足，导致腐殖质市场的供应、需求和预算逐渐增加。鉴于木质素和HS的类似结构，人工调节腐殖化（ARH）在定向控制木质素的氧化裂解和/或木质素前体的自由基共聚方面具有巨大的潜力，以生产可与木质素相媲美的重新组装的低聚物和/或聚合物。 HS 的功能和功效。在此，创新性地提出了不同的 ARH 策略来应对危险化学品并创建类腐殖质生物刺激剂（H-LB）。我们简要描述了天然HS的特征和功能，总结了木质素及其前体ARH的最新研究方法和机制。其中，生物堆肥、漆酶催化、白腐真菌降解、基于芬顿的高级氧化和水热腐殖化等ARH途径在治理有害底物、增强碳封存、产生H-LB和实践可持续农业方面相对突出。 。此外，还阐明了 H-LB 促进作物生长的机制。调节腐殖化途径的进展可能会通过丰富的木质素及其小衍生物解决原位和异位ARH的技术瓶颈，这对于净化污染物、减少CO ₂ 排放和富集H具有重要意义。 -农业生态系统中的LB。