The Front Cover's dandelion represents the lipase-catalyzed kinetic resolution of racemic tertiary alcohols. The fluff is deemed a serine residue, bearing an acyl moiety, at the active center of an acyl-enzyme intermediate. When R-alcohols on the spring breeze come into contact with the active center, they are converted to the corresponding esters and fly away on the wind, just like dandelion seeds. More information can be found in the Research Article by H. Gröger, S. Akai and co-workers (DOI: 10.1002/ejoc.202400242).

中文翻译：

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封面：用来自南极洲念珠菌的脂肪酶 A 动力学拆分环状叔醇（Eur. J. Org. Chem. 21/2024）


封面的蒲公英代表外消旋叔醇的脂肪酶催化动力学拆分。绒毛被认为是丝氨酸残基，在酰基酶中间体的活性中心带有酰基部分。当春风中的R-醇与活性中心接触时，就会转化为相应的酯并随风飞走，就像蒲公英的种子一样。更多信息请参阅 H. Gröger、S. Akai 及其同事的研究文章 (DOI: 10.1002/ejoc.202400242)。