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Author Correction: The senescent methylome and its relationship with cancer, ageing and germline genetic variation in humans
Genome Biology ( IF 10.1 ) Pub Date : 2024-06-10 , DOI: 10.1186/s13059-024-03295-7
Robert Lowe 1 , Marita G Overhoff 1 , Sreeram V Ramagopalan 1 , James C Garbe 2 , James Koh 3 , Martha R Stampfer 2 , David H Beach 1 , Vardhman K Rakyan 1 , Cleo L Bishop 1
Affiliation  

Author Correction: Genome Biol 16, 194 (2015)

https://doi.org/10.1186/s13059-015-0748-4


Following publication of the original article [1], the authors reported two errors in Fig. 1B and Fig. 2B.

1. The two EP + siGLO and DS + siGLO brightfield/β-gal images from Fig. 2A were accidentally duplicated in Fig. 1B. The images in Fig. 2A are correct.

The images in Fig. 1B are replaced with representative images of untransfected EP and DS cells. The incorrect and the correct figure are given below.

The incorrect Fig. 1:

figure a

The correct Fig. 1:

figure b

The replacement of these images does not change any of the other data in this figure, nor the conclusion of this figure.

2. The authors also noticed that the panels in Fig. 2B labelled with “DS” were incorrectly labelled. The bar charts and figure legend correctly state that these images are “DS + siGLO” images. These panels are now relabelled as “DS + siGLO”.

This proposed relabelling does not change any of the other data in this figure, nor the conclusion of Fig. 2B. The incorrect and the correct figure are given below.

The incorrect Fig. 2:

figure c

The correct Fig. 2:

figure d

In both instances, these errors do not change any data associated with these figures, nor do they change the conclusions of the corresponding figures and the paper.

  1. Lowe R, Overhoff MG, Ramagopalan SV, et al. The senescent methylome and its relationship with cancer, ageing and germline genetic variation in humans. Genome Biol. 2015;16:194. https://doi.org/10.1186/s13059-015-0748-4.

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Authors and Affiliations

  1. The Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, 4 Newark Street, London, E1 2AT, UK

    Robert Lowe, Marita G. Overhoff, Sreeram V. Ramagopalan, David H. Beach, Vardhman K. Rakyan & Cleo L. Bishop

  2. Life Science Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA

    James C. Garbe & Martha R. Stampfer

  3. Division of Surgical Sciences, Department of Surgery, Duke University Medical School, Durham, NC, 27710, USA

    James Koh

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  8. Vardhman K. RakyanView author publications

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Corresponding authors

Correspondence to Vardhman K. Rakyan or Cleo L. Bishop.

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Lowe, R., Overhoff, M.G., Ramagopalan, S.V. et al. Author Correction: The senescent methylome and its relationship with cancer, ageing and germline genetic variation in humans. Genome Biol 25, 150 (2024). https://doi.org/10.1186/s13059-024-03295-7

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中文翻译：

作者更正：衰老甲基化组及其与人类癌症、衰老和种系遗传变异的关系


作者更正：基因组生物学 16, 194 (2015)

https://doi.org/10.1186/s13059-015-0748-4



原文章 [1] 发表后，作者报告了图 1B 和图 2B 中的两个错误。


1. 图 2A 中的两张 EP + siGLO 和 DS + siGLO 明场/β-gal 图像在图 1B 中意外重复。图 2A 中的图像是正确的。


图 1B 中的图像替换为未转染的 EP 和 DS 细胞的代表性图像。错误的和正确的数字如下所示。

 错误的图1：

figure a

 正确的图1：

figure b


这些图像的替换不会改变该图中的任何其他数据，也不会改变该图的结论。


2. 作者还注意到图2B中标有“DS”的面板被错误地标记。条形图和图形图例正确地表明这些图像是“DS + siGLO”图像。这些面板现在重新标记为“DS + siGLO”。


这个提议的重新标记不会改变该图中的任何其他数据，也不会改变图 2B 的结论。错误的和正确的数字如下所示。

 错误的图2：

figure c

 正确的图2：

figure d


在这两种情况下，这些错误不会改变与这些图相关的任何数据，也不会改变相应图和论文的结论。


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 作者和单位


  1. 暴雪研究所、巴茨和伦敦医学与牙科学院、伦敦玛丽女王大学，地址：4 Newark Street, London, E1 2AT, UK


    罗伯特·洛 (Robert Lowe)、玛丽塔·G·奥弗霍夫 (Marita G. Overhoff)、斯里拉姆·V·拉马戈帕兰 (Sreeram V. Ramagopalan)、大卫·H·比奇 (David H. Beach)、瓦德曼·K·拉基安 (Vardhman K. Rakyan) 和克莱奥·L·毕肖普 (Cleo L. Bishop)


  2. 劳伦斯伯克利国家实验室生命科学部，伯克利，加利福尼亚州，94720，美国


    詹姆斯·C·加布和玛莎·R·斯坦普弗


  3. 杜克大学医学院外科科学部，北卡罗来纳州达勒姆，27710，美国

     詹姆斯·许

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通讯作者：Vardhman K. Rakyan 或 Cleo L. Bishop。


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Lowe, R.、Overhoff, MG、Ramagopalan, SV等人。作者更正：衰老甲基化组及其与人类癌症、衰老和种系遗传变异的关系。基因组生物学25 , 150 (2024)。 https://doi.org/10.1186/s13059-024-03295-7

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