当前位置: X-MOL 学术Dev. Cell › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
The microtubular preprophase band recruits Myosin XI to the cortical division site to guide phragmoplast expansion during plant cytokinesis
Developmental Cell ( IF 10.7 ) Pub Date : 2024-06-06 , DOI: 10.1016/j.devcel.2024.05.015
Calvin Haoyuan Huang 1 , Felicia Lei Peng 1 , Yuh-Ru Julie Lee 1 , Bo Liu 1
Affiliation  

In plant vegetative tissues, cell division employs a mitotic microtubule array called the preprophase band (PPB) that marks the cortical division site. This transient cytoskeletal array imprints the spatial information to be read by the cytokinetic phragmoplast at later stages of mitotic cell division. In , we discovered that the PPB recruited the Myosin XI motor MYA1/Myo11F to the cortical division site, where it joined microtubule-associated proteins and motors to form a ring of prominent cytoskeletal assemblies that received the expanding phragmoplast. Such a myosin localization pattern at the cortical division site was dependent on the POK1/2 Kinesin-12 motors. This regulatory function of MYA1/Myo11F in phragmoplast guidance was dependent on intact actin filaments. The discovery of these cytoskeletal motor assemblies pinpoints a mechanism underlying how two dynamic cytoskeletal networks work in concert to govern PPB-dependent division plane orientation in flowering plants.

中文翻译:


微管前前期带将肌球蛋白 XI 募集到皮质分裂部位,以指导植物胞质分裂过程中的 phragmoplast 扩张



在植物营养组织中,细胞分裂采用称为前前期带 (PPB) 的有丝分裂微管阵列,它标志着皮质分裂部位。这种瞬时细胞骨架阵列印记了细胞动力学 phragmoplast 在有丝分裂细胞分裂的后期要读取的空间信息。在 中,我们发现 PPB 将肌球蛋白 XI 马达 MYA1/Myo11F 募集到皮质分裂部位,在那里它连接微管相关蛋白和马达,形成一圈突出的细胞骨架组件,这些细胞骨架组件接收膨胀的 phragmoplast。皮质分裂部位的这种肌球蛋白定位模式依赖于 POK1/2 驱动蛋白-12 马达。MYA1/Myo11F 在 phragmoplast 引导中的这种调节功能依赖于完整的肌动蛋白丝。这些细胞骨架运动组件的发现指出了两个动态细胞骨架网络如何协同工作以控制开花植物中 PPB 依赖性分裂平面方向的潜在机制。
更新日期:2024-06-06
down
wechat
bug