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From stem cells to regulatory T cells: A tale of plasticity
Cell Stem Cell ( IF 19.8 ) Pub Date : 2024-06-06 , DOI: 10.1016/j.stem.2024.05.002
Mehek Ningoo 1 , Miguel Fribourg 1
Affiliation  

In this issue, Yano et al.1 present a method to obtain suppressive regulatory T (Treg) cells from human induced pluripotent stem cells (hiPSCs). This approach has the potential to address the low Treg cell yields of current ex vivo Treg cell expansion and induction protocols, an unmet challenge for autologous Treg cell treatments.



中文翻译:


从干细胞到调节性 T 细胞:可塑性的故事



在本期中 Yano 等人。图 1提出了一种从人诱导多能干细胞 (hiPSC) 中获得抑制性调节性 T (Treg) 细胞的方法。这种方法有可能解决当前离体Treg 细胞扩增和诱导方案中 Treg 细胞产量低的问题,这是自体 Treg 细胞治疗中尚未解决的挑战。

更新日期:2024-06-06
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