Chimeric antigen receptor (CAR) macrophages have broadened the landscape of anti-cancer immunotherapies to combat solid malignancies. Shah et al. introduce CARs to facilitate a CAR macrophage therapy, which aims to recruit and activate T/natural killer cells, further strengthening the overall immune response to decrease pancreatic cancer burden and metastatic spreading.

中文翻译：

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CAR巨噬细胞调节抗癌疗法的免疫交响曲

嵌合抗原受体（CAR）巨噬细胞拓宽了抗癌免疫疗法的前景，以对抗实体恶性肿瘤。沙阿等人。引入 CAR 来促进 CAR 巨噬细胞疗法，该疗法旨在招募和激活 T/自然杀伤细胞，进一步加强整体免疫反应，以减少胰腺癌负担和转移扩散。