当前位置: X-MOL 学术Cell Stem Cell › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Greasing the machinery toward maturation of stem cell-derived β cells
Cell Stem Cell ( IF 19.8 ) Pub Date : 2024-06-06 , DOI: 10.1016/j.stem.2024.05.001
Christos Karampelias , Heiko Lickert

Getting mature and functional stem cell-derived, insulin-producing β cells is an important step for disease modeling, drug screening, and cell replacement therapy. In this issue, Hua et al.1 used single-cell multiomics analysis coupled with chemical screening to identify a crucial role for ceramides in generating mature stem cell-derived β cells.



中文翻译:


为干细胞衍生的 β 细胞的成熟提供动力



获得成熟且有功能的干细胞衍生的、产生胰岛素的β细胞是疾病建模、药物筛选和细胞替代治疗的重要一步。在本期中,华等人。 1 使用单细胞多组学分析结合化学筛选来确定神经酰胺在生成成熟干细胞衍生的 β 细胞中的关键作用。

更新日期:2024-06-06
down
wechat
bug