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A mobile home for T cells
Nature Materials ( IF 37.2 ) Pub Date : 2024-06-04 , DOI: 10.1038/s41563-024-01906-z Kewen Lei , Darrell J. Irvine
Nature Materials ( IF 37.2 ) Pub Date : 2024-06-04 , DOI: 10.1038/s41563-024-01906-z Kewen Lei , Darrell J. Irvine
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Lyophilized lymph nodes are a natural scaffold to deliver chimeric antigen receptor (CAR) T cells to tumour resection sites, where they serve as a natural T cell-supporting niche and enhance CAR T cell efficacy in reducing recurrence in preclinical tumour resection models.
中文翻译:
T细胞的移动之家
冻干淋巴结是一种天然支架,可将嵌合抗原受体 (CAR) T 细胞递送至肿瘤切除部位,在肿瘤切除部位充当天然 T 细胞支持生态位,并增强 CAR T 细胞在减少临床前肿瘤切除模型复发方面的功效。
更新日期:2024-06-04
中文翻译:
![](https://scdn.x-mol.com/jcss/images/paperTranslation.png)
T细胞的移动之家
冻干淋巴结是一种天然支架,可将嵌合抗原受体 (CAR) T 细胞递送至肿瘤切除部位,在肿瘤切除部位充当天然 T 细胞支持生态位,并增强 CAR T 细胞在减少临床前肿瘤切除模型复发方面的功效。