The use of cystatin C-inclusive equations will continue to propagate the unnecessary overdiagnosis of chronic kidney disease (CKD) in older people. Cystatin C is less biologically specific for CKD than is serum creatinine, inflates the risks of adverse outcomes compared to measured glomerular filtration rate, and does not establish chronicity at a single time point.

中文翻译：

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胱抑素 C 与老年人 CKD 的误诊


使用包含胱抑素 C 的方程将继续在老年人中传播对慢性肾病 (CKD) 的不必要的过度诊断。与血清肌酐相比，胱抑素 C 对 CKD 的生物学特异性较低，与测量的肾小球滤过率相比，会增加不良结果的风险，并且不能在单个时间点建立慢性病。