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Antibiotic calcium sulphate beads lower the bacterial burden and prevent infection in a mouse model of periprosthetic joint infection.
The Bone & Joint Journal ( IF 4.9 ) Pub Date : 2024-06-01 , DOI: 10.1302/0301-620x.106b6.bjj-2023-1175.r1 Christopher M Hart 1 , Benjamin V Kelley 1 , Zeinab Mamouei 1 , Amr Turkmani 1 , Micah Ralston 1 , Michael Arnold 1 , Nicholas M Bernthal 1 , Adam A Sassoon 1
The Bone & Joint Journal ( IF 4.9 ) Pub Date : 2024-06-01 , DOI: 10.1302/0301-620x.106b6.bjj-2023-1175.r1 Christopher M Hart 1 , Benjamin V Kelley 1 , Zeinab Mamouei 1 , Amr Turkmani 1 , Micah Ralston 1 , Michael Arnold 1 , Nicholas M Bernthal 1 , Adam A Sassoon 1
Affiliation
Delayed postoperative inoculation of orthopaedic implants with persistent wound drainage or bacterial seeding of a haematoma can result in periprosthetic joint infection (PJI). The aim of this in vivo study was to compare the efficacy of vancomycin powder with vancomycin-eluting calcium sulphate beads in preventing PJI due to delayed inoculation.
中文翻译:
抗生素硫酸钙珠可降低假体周围关节感染小鼠模型中的细菌负荷并预防感染。
矫形植入物的术后延迟接种以及持续的伤口引流或血肿的细菌播种可能会导致假体周围关节感染(PJI)。这项体内研究的目的是比较万古霉素粉末与万古霉素洗脱硫酸钙珠在预防延迟接种所致 PJI 方面的功效。
更新日期:2024-06-01
中文翻译:
抗生素硫酸钙珠可降低假体周围关节感染小鼠模型中的细菌负荷并预防感染。
矫形植入物的术后延迟接种以及持续的伤口引流或血肿的细菌播种可能会导致假体周围关节感染(PJI)。这项体内研究的目的是比较万古霉素粉末与万古霉素洗脱硫酸钙珠在预防延迟接种所致 PJI 方面的功效。