ObjectiveTo describe the incidence, and sociodemographic and clinical factors associated with preterm birth and perinatal mortality in Nigeria.DesignSecondary analysis of data collected through the Maternal Perinatal Database for Quality, Equity and Dignity (MPD‐4‐QED) Programme.SettingData from births in 54 referral‐level hospitals across Nigeria between 1 September 2019 and 31 August 2020.PopulationA total of 69 698 births.MethodsMultilevel modelling was used to determine the factors associated with preterm birth and perinatal mortality.Outcome measuresPreterm birth and preterm perinatal mortality.ResultsOf 62 383 live births, 9547 were preterm (153 per 1000 live births). Maternal age (<20 years – adjusted odds ratio [aOR] 1.52, 95% CI 1.36–1.71; >35 years – aOR 1.23, 95% CI 1.16–1.30), no formal education (aOR 1.68, 95% CI 1.54–1.84), partner not gainfully employed (aOR 1.94, 95% CI 1.61–2.34) and no antenatal care (aOR 2.62, 95% CI 2.42–2.84) were associated with preterm births. Early neonatal mortality for preterm neonates was 47.2 per 1000 preterm live births (451/9547). Father's occupation (manual labour aOR 1.52, 95% CI 1.20–1.93), hypertensive disorders of pregnancy (aOR 1.37, 95% CI 1.02–1.83), no antenatal care (aOR 2.74, 95% CI 2.04–3.67), earlier gestation (28 to <32 weeks – aOR 2.94, 95% CI 2.15–4.10; 32 to <34 weeks – aOR 1.80, 95% CI 1.3–2.44) and birthweight <1000 g (aOR 21.35, 95% CI 12.54–36.33) were associated with preterm perinatal mortality.ConclusionsPreterm birth and perinatal mortality in Nigeria are high. Efforts should be made to enhance access to quality health care during pregnancy, delivery and the neonatal period, and improve the parental socio‐economic status.

中文翻译：

---

尼日利亚高等教育机构早产的决定因素和结果


目的描述尼日利亚与早产和围产期死亡率相关的发病率、社会人口统计学和临床​​因素。设计对通过孕产妇围产期质量、公平和尊严数据库 (MPD-4-QED) 项目收集的数据进行二次分析。设置来自 54 个国家的出生数据2019年9月1日至2020年8月31日期间尼日利亚各地的转诊级医院。人口共有69 698名新生儿。方法采用多层次模型确定与早产和围产儿死亡率相关的因素。结果指标早产和早产围产儿死亡率。结果 62 383名活产者其中 9547 名早产儿（每 1000 名活产儿 153 名）。母亲年龄（<20 岁 - 调整优势比 [aOR] 1.52，95% CI 1.36–1.71；>35 岁 - aOR 1.23，95% CI 1.16–1.30），未受过正规教育（aOR 1.68，95% CI 1.54–1.84） ）、伴侣无报酬就业（aOR 1.94，95% CI 1.61–2.34）和无产前护理（aOR 2.62，95% CI 2.42–2.84）与早产相关。早产儿的早期死亡率为每 1000 名早产活产儿 47.2 人 (451/9547)。父亲的职业（体力劳动 aOR 1.52，95% CI 1.20–1.93）、妊娠期高血压疾病（aOR 1.37，95% CI 1.02–1.83）、无产前护理（aOR 2.74，95% CI 2.04–3.67）、早孕（ 28 至 <32 周 – aOR 2.94，95% CI 2.15–4.10；32 至 <34 周 – aOR 1.80，95% CI 1.3–2.44）与出生体重 <1000 g（aOR 21.35，95% CI 12.54–36.33）相关结论尼日利亚的早产和围产儿死亡率很高。努力提高孕产期和新生儿期优质卫生保健水平，提高父母社会经济地位。