All-in-one Hangzhou Protocol: killing four birds with one stone,Cell Research

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All-in-one Hangzhou Protocol: killing four birds with one stone
Cell Research ( IF 28.1 ) Pub Date : 2024-05-31 , DOI: 10.1038/s41422-024-00983-8
Haopeng Wang _{1,

2,

3} , Shizhen Qiu _{1,

4} , Mohamad Mohty ₅

Affiliation

In a recent study published in The New England Journal of Medicine, researchers developed an innovative “all-in-one” treatment protocol that combines CD7 chimeric antigen receptor T-cell therapy with subsequent haploidentical hematopoietic stem cell transplantation. This approach significantly advances the treatment of CD7⁺ hematological malignancies by eliminating the need for myeloablative chemotherapy and immunosuppressants for graft-versus-host disease prophylaxis.

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