Physical approaches based on irradiation provide advances for the prevention and treatment of viral infections, while recognizing that certain chemical inactivation techniques demonstrate significant effectiveness alongside physical methods. By generating resonant vibrations of complete virus particles, which are in the GHz range and quite high compared to that of human cells, viruses can be inactivated. Therefore, exposure to ultrasound waves or non-thermal microwaves with a suitable resonant frequency oscillating electric field holds the potential to neutralize the virus particle with no damage to human. The deactivation mechanism could be a result of the mechanical effect or oxidation stress, and in this article, we discuss the elucidation of these effects on the virus' structure. We also explore the current state and future prospects of the anti-viral methods based on acoustic cavitation via ultrasound and non-thermal microwave, addressing critical needs in virology.

中文翻译：

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通过匹配振动共振灭活病毒


基于辐照的物理方法为预防和治疗病毒感染提供了进步，同时认识到某些化学灭活技术与物理方法相比表现出显着的有效性。通过产生完整病毒颗粒的共振（其频率在 GHz 范围内，与人体细胞相比相当高），病毒可以被灭活。因此，暴露于具有合适共振频率振荡电场的超声波或非热微波有可能中和病毒颗粒而不会对人体造成伤害。失活机制可能是机械效应或氧化应激的结果，在本文中，我们讨论了这些对病毒结构的影响的阐明。我们还探讨了基于超声波和非热微波的声空化抗病毒方法的现状和未来前景，以满足病毒学的关键需求。