Paragraph above Figure 31, the text in following lines: Inducing cell death via DNA damage using chemo- or radiotherapy is a common strategy in the treatment of cancer, with collateral damage affecting and killing healthy cells.^348,349 Boron neutron capture therapy (BNCT) uses low-LET X-rays, making it advantageous as it mitigates potential lethal radiation that could affect healthy tissue.^350–353 It should be replaced by the following: Inducing cell death via DNA damage using chemo- or radiotherapy is a common strategy in the treatment of cancer, with collateral damage affecting and killing healthy cells.^348,349 Boron neutron capture therapy (BNCT), which is based on the ¹⁰B interaction with low-energy (thermal) neutrons to produce highly energetic, is a dual treatment modality that can selectively target neoplastic tissue (Coderre, J. A.; Morris, G. M. The radiation biology of boron neutron capture therapy. Radiat. Res. 1999, 151, 1–18). The thermal neutrons used in this therapy typically possess energy levels insufficient to harm tumor or normal tissue directly, as they fall below 0.4 eV. However, the interaction between thermal neutrons and ¹⁰B within the tumor cells results in the release of high-linear energy transfer (LET) radiation (¹⁰B + ¹n → ⁷Li + ⁴He + 2.79 MeV), which is potent enough to induce cell death. Importantly, the short-range of the particles generated by the neutron capture reaction (less than 10 μm) helps confine the damage to cells containing ¹⁰B, minimizing collateral harm to surrounding tissues. BNCT makes the cancer treatment advantageous, as it mitigates potential lethal radiation that could affect healthy tissue.^350–353 This article has not yet been cited by other publications.

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对“含硼化合物的兴起：合成、药物化学和新兴药理学的进展”的更正


图 31 上方的段落，文本如下：使用化疗或放疗通过 DNA 损伤诱导细胞死亡是治疗癌症的常见策略，附带损伤会影响和杀死健康细胞。 ^348,349硼中子捕获疗法 (BNCT) 使用低 LET X 射线，因此具有优势，因为它可以减轻可能影响健康组织的潜在致命辐射。 ^350–353应替换为以下内容：使用化疗或放疗通过 DNA 损伤诱导细胞死亡是治疗癌症的常见策略，附带损害会影响和杀死健康细胞。 ^348,349硼中子捕获疗法 (BNCT) 基于¹⁰ B 与低能（热）中子相互作用产生高能，是一种双重治疗方式，可以选择性地靶向肿瘤组织（Coderre，JA；Morris，GM）硼中子俘获疗法的放射生物学研究。1999，151，1-18 ）。该疗法中使用的热中子通常具有不足以直接伤害肿瘤或正常组织的能量水平，因为它们低于 0.4 eV。然而，热中子与肿瘤细胞内¹⁰ B 之间的相互作用会导致释放高线性能量转移 (LET) 辐射 ( ¹⁰ B + ¹ n → ⁷ Li + ⁴ He + 2.79 MeV)，其强度足以诱导细胞死亡。重要的是，中子捕获反应产生的短程粒子（小于 10 μm）有助于限制对含有¹⁰ B 的细胞的损害，从而最大限度地减少对周围组织的附带伤害。 BNCT 使癌症治疗具有优势，因为它可以减轻可能影响健康组织的潜在致命辐射。 ^350–353本文尚未被其他出版物引用。