Macromolecules are involved in myriads of interactions that regulate their cellular function. While years of structural biology progress was built by reducing this complexity, a molecular understanding of biological processes requires the characterization of ever larger and more dynamic molecular assemblies. Cryo-electron microscopy is rising to this challenge.

中文翻译：

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增强结构生物学研究的复杂性


大分子参与调节其细胞功能的无数相互作用。虽然结构生物学多年来的进步是通过降低这种复杂性而取得的，但对生物过程的分子理解需要对更大、更动态的分子组装体进行表征。冷冻电子显微镜正在迎接这一挑战。