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Bump-hole ZDHHCs
Nature Chemical Biology ( IF 12.9 ) Pub Date : 2024-05-28 , DOI: 10.1038/s41589-024-01634-0
Tong Lan 1 , Bryan C Dickinson 1
Nature Chemical Biology ( IF 12.9 ) Pub Date : 2024-05-28 , DOI: 10.1038/s41589-024-01634-0
Tong Lan 1 , Bryan C Dickinson 1
Affiliation
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The ZDHHC family of palmitoyl transferases lipidates numerous protein targets, but the paucity of selective inhibitors has hindered their target profiling. A generalized chemical genetic system can now map the protein targets of individual ZDHHC family members.
中文翻译:
凹凸孔 ZDHHC
ZDHHC 棕榈酰基转移酶家族可脂化许多蛋白质靶标,但选择性抑制剂的缺乏阻碍了它们的靶标分析。通用化学遗传系统现在可以绘制单个 ZDHHC 家族成员的蛋白质靶点图谱。
更新日期:2024-05-28
中文翻译:

凹凸孔 ZDHHC
ZDHHC 棕榈酰基转移酶家族可脂化许多蛋白质靶标,但选择性抑制剂的缺乏阻碍了它们的靶标分析。通用化学遗传系统现在可以绘制单个 ZDHHC 家族成员的蛋白质靶点图谱。