Psoriatic arthritis (PsA) is a chronic, potentially debilitating inflammatory arthritis often associated with psoriasis. Understanding the epidemiology of PsA across diverse populations can provide valuable insights into its global burden and the role of genetic and environmental factors. This study aimed to estimate PsA’s temporal trends, prevalence, and incidence, while assessing variations in age, gender, and ethnicity in Israel from 2016 to 2022. Data were sourced from the Clalit Health Services (CHS) database, covering over half of the Israeli population. Algorithm-based definitions for PsA and psoriasis cases were used. Demographic factors, including age, gender, socioeconomic status (SES), ethnicity, urban/rural residence, BMI, and smoking status, were analyzed. Standardized prevalence and incidence rates were calculated. Logistic regression analyses examined associations of sociodemographic variables with PsA. In 2022, the prevalence of PsA was 0.221%, with an incidence rate of 13.54 per 100,000 population. This prevalence has tripled since 2006, reflecting a rising trend in PsA over time. Females exhibited a higher prevalence (1.15; 95%CI 1.09–1.21), and PsA was more common in Jewish individuals (1.58; 95%CI 1.45–1.71) those with higher SES (1.4; 95% CI 1.31, 1.5), and those with obesity (2.17; 95%CI 2.04–2.31). This comprehensive population-based study pointed to an increase prevalence of PsA, emphasizing the rising healthcare demands and economic burden faced by this patient population. Further research is essential to delve into the factors driving these trends.

中文翻译：

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银屑病关节炎的流行病学趋势：一项基于人群的综合研究


银屑病关节炎 (PsA) 是一种慢性、可能使人衰弱的炎症性关节炎，通常与银屑病相关。了解不同人群中银屑病关节炎的流行病学可以为了解其全球负担以及遗传和环境因素的作用提供有价值的见解。本研究旨在估计 2016 年至 2022 年以色列 PsA 的时间趋势、患病率和发病率，同时评估年龄、性别和种族的变化。数据来源于 Clalit Health Services (CHS) 数据库，覆盖了一半以上的以色列人人口。使用基于算法的银屑病关节炎和银屑病病例定义。分析了人口统计因素，包括年龄、性别、社会经济地位（SES）、种族、城乡居住情况、BMI和吸烟状况。计算标准化患病率和发病率。逻辑回归分析检查了社会人口统计学变量与 PsA 的关联。 2022年，银屑病关节炎患病率为0.221%，发病率为每10万人13.54例。自 2006 年以来，这一患病率增加了两倍，反映出随着时间的推移，银屑病关节炎呈上升趋势。女性患病率较高 (1.15; 95% CI 1.09–1.21)，银屑病关节炎在犹太人中更常见 (1.58; 95% CI 1.45–1.71)，而那些具有较高 SES 的人 (1.4; 95% CI 1.31, 1.5)，肥胖者（2.17；95%CI 2.04–2.31）。这项基于人群的综合研究指出银屑病关节炎的患病率有所增加，强调了该患者群体面临的医疗保健需求和经济负担不断增加。进一步的研究对于深入研究驱动这些趋势的因素至关重要。