Metastable zone width (MSZW) and induction time data for isonicotinamide (INA) in various solvents, including methanol, acetone, acetonitrile, and ethyl acetate, were experimentally measured using a turbidity probe. For the MSZW data, the interfacial energy and pre-exponential factor were determined and compared based on classical nucleation theory (CNT) using the integral model, the linearized integral model, and the classical 3D nucleation theory approach, respectively. For the induction time data, the interfacial energy and pre-exponential factor were determined based on CNT using the conventional method. The nucleation criteria at the nucleation point in derivation of various models were examined in detail. The obtained interfacial energy and pre-exponential factor from the MSZW data for INA in each solvent were compared with those from the induction time data.

中文翻译：

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根据诱导时间和介稳区宽度数据比较异烟酰胺在各种溶剂中的界面能和指前因子


使用浊度探针通过实验测量异烟酰胺 (INA) 在各种溶剂（包括甲醇、丙酮、乙腈和乙酸乙酯）中的亚稳区宽度 (MSZW) 和诱导时间数据。对于 MSZW 数据，基于经典成核理论 (CNT)，分别使用积分模型、线性化积分模型和经典 3D 成核​​理论方法确定并比较了界面能和指前因子。对于诱导时间数据，使用传统方法基于CNT确定界面能和指前因子。详细研究了各种模型推导中成核点的成核标准。将每种溶剂中 INA 的 MSZW 数据获得的界面能和指前因子与诱导时间数据获得的界面能和指前因子进行比较。