A novel BSL-2 Lassa virus reverse genetics system modelling the complete viral life cycle,Emerging Microbes & Infections

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A novel BSL-2 Lassa virus reverse genetics system modelling the complete viral life cycle
Emerging Microbes & Infections ( IF 8.4 ) Pub Date : 2024-06-10 , DOI: 10.1080/22221751.2024.2356149
Xiaoyou Hu _{1,

2} , Xu Bai _{1,

2} , Fangling Tian _{1,

2} , Yifan Xing _{1,

2} , Yi Shi ₃ , Yimin Tong _{1,

2} , Jin Zhong _{1,

2,

4}

Affiliation

Lassa virus (LASV), a risk-group 4 pathogen, must be handled in biosafety level-4 (BSL-4) conditions, thereby limiting its research and antiviral development. Here, we developed a novel LASV revers...

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