Currently, autologous platelet concentrates (APCs) are frequently used for soft‐ and hard‐tissue regeneration, not only within the oral cavity, but also extra‐orally including chronic wounds, burns, joints, dermatological conditions, among others. The benefits of APCs are largely influenced by the treatment strategy but also their preparation. This paper therefore discusses in detail: the physical properties of blood cells, the basic principles of blood centrifugation, the impact of the centrifugation protocol (rotations/revolutions per minute, g‐force, variation between centrifuges), the importance of timing during the preparation of APCs, the impact of the inner surface of the blood tubes, the use/nonuse of anticoagulants within APC tubes, the impact of the patient's hematocrit, age, and gender, as well as the important requirements for an optimal centrifugation protocol. All these variables indeed have a significant impact on the clinical outcome of APCs.

中文翻译：

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血液离心的基本原理


目前，自体血小板浓缩物（APC）经常用于软组织和硬组织再生，不仅在口腔内，而且在口腔外，包括慢性伤口、烧伤、关节、皮肤病等。 APC 的益处在很大程度上受到治疗策略及其制备的影响。因此，本文详细讨论了：血细胞的物理特性、血液离心的基本原理、离心方案的影响（每分钟旋转/转数、重力、离心机之间的变化）、制备过程中计时的重要性APC 的影响、血管内表面的影响、APC 管内使用/不使用抗凝剂、患者血细胞比容、年龄和性别的影响，以及最佳离心方案的重要要求。所有这些变量确实对 APC 的临床结果有重大影响。