We identified U.S. reports of postmenopausal bleeding in the VAERS (Vaccine Adverse Event Reporting System) between December 13, 2020, and December 13, 2021. Among 711,224 VAERS reports after coronavirus disease 2019 (COVID-19) vaccination, during our study period, we identified 554 presumptive postmenopausal bleeding reports; 434 were further classified as verified based on data abstracted from reports and medical records, when available. In the United States, by December 14, 2021, 58.8 million women aged 50 years or older had received at least one dose of a COVID-19 vaccine, corresponding to approximately seven verified VAERS postmenopausal bleeding reports per 1 million women aged 50 years or older who received a COVID-19 vaccine. Reports of postmenopausal bleeding after COVID-19 vaccination in VAERS were rare, and causes of postmenopausal bleeding based on medical record review were consistent with known causes of postmenopausal bleeding.

中文翻译：

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2019 年冠状病毒病 (COVID-19) 疫苗接种后绝经后出血：疫苗不良事件报告系统。


我们在 VAERS（疫苗不良事件报告系统）中确定了 2020 年 12 月 13 日至 2021 年 12 月 13 日期间美国绝经后出血的报告。在我们的研究期间，在 2019 年冠状病毒病 (COVID-19) 疫苗接种后的 711,224 份 VAERS 报告中，我们发现确定了 554 份推定绝经后出血报告；根据从报告和医疗记录中提取的数据（如果有），434 例被进一步分类为已验证。在美国，截至 2021 年 12 月 14 日，5880 万名 50 岁或以上女性已接种至少一剂 COVID-19 疫苗，相当于每 100 万名 50 岁或以上女性中约有 7 份经过验证的 VAERS 绝经后出血报告接种了 COVID-19 疫苗的人。 VAERS 中接种 COVID-19 后出现绝经后出血的报告很少见，并且根据病历审查得出的绝经后出血原因与已知的绝经后出血原因一致。