A series of novel derivatives of triazolo[1,5-a]pyrimidine are designed and synthesized by a three-component reaction of N,N'-(sulfonylbis(4,1-phenylene))bis(3-oxobutanamide), aldehydes and 3-methyl-1H-1,2,4-triazol-5-amine. The use of silica sulfuric acid (SiO-SOH) as a catalyst afforded a series of N,N'-(sulfonylbis(4,1-phenylene))bis(3,7-dimethyl-5-aryl-5,8-dihydro-[1,2,4]triazolo[4,3-a]pyrimidine-6-carboxamide) derivatives as the desired products (a-a) in high yields in DMF as solvent as well as under solvent-free conditions. All reactions were performed in ultrasonic irradiation conditions.

中文翻译：

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超声辐照条件下多组分制备新型三唑并[1,5-a]嘧啶衍生物


通过N,N'-(磺酰基双(4,1-亚苯基))双(3-氧代丁酰胺)、醛和化合物的三组分反应，设计合成了一系列新型三唑并[1,5-a]嘧啶衍生物。 3-甲基-1H-1,2,4-三唑-5-胺。使用二氧化硅硫酸(SiO-SOH)作为催化剂，得到一系列N,N'-(磺酰基双(4,1-亚苯基))双(3,7-二甲基-5-芳基-5,8-二氢) -[1,2,4]三唑并[4,3-a]嘧啶-6-甲酰胺)衍生物作为所需产物(a-a)在作为溶剂的DMF以及无溶剂条件下以高收率获得。所有反应均在超声波照射条件下进行。