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Bridging the gap: Integrating exercise mimicry into chronic disease management through suppressing chronic inflammation
Journal of Advanced Research ( IF 11.4 ) Pub Date : 2024-05-03 , DOI: 10.1016/j.jare.2024.04.034
Mohammad Nasb 1 , Fengxing Li 1 , Lamis Dayoub 2 , Tong Wu 1 , Minhui Wei 1 , Ning Chen 1
Affiliation  

Chronic inflammation is a common hallmark of many chronic diseases. Although exercise holds paramount importance in preventing and managing chronic diseases, adherence to exercise programs can be challenging for some patients. Consequently, there is a pressing need to explore alternative strategies to emulate the anti-inflammatory effects of exercise for chronic diseases. This review explores the emerging role of green tea bioactive components as potential mitigators of chronic inflammation, offering insights into their capacity to mimic the beneficial effects of exercise. We propose that bioactive components in green tea are promising agents for suppressing chronic inflammation, suggesting their unique capability to replicate the health benefits of exercise. This review focuses on several key concepts, including chronic inflammation and its role in chronic diseases, the anti-inflammatory effects of regular exercise, and bioactive components in green tea responsible for its health benefits. It elaborates on scientific evidence supporting the anti-inflammatory properties of green tea bioactive components, such as epigallocatechin gallate (EGCG), and theorizes how these bioactive components might replicate the effects of exercise at a molecular level. Through a comprehensive analysis of current research, this review proposes a novel perspective on the application of green tea as a potential intervention strategy to suppress chronic inflammation, thereby extending the benefits akin to those achieved through exercise.

中文翻译:


弥合差距:通过抑制慢性炎症将运动模仿纳入慢性病管理



慢性炎症是许多慢性疾病的共同特征。尽管运动对于预防和管理慢性病至关重要,但坚持运动计划对某些患者来说可能具有挑战性。因此,迫切需要探索替代策略来模拟运动对慢性疾病的抗炎作用。这篇综述探讨了绿茶生物活性成分作为慢性炎症潜在缓解剂的新兴作用,深入了解它们模拟运动有益效果的能力。我们认为绿茶中的生物活性成分是抑制慢性炎症的有前景的药物,这表明它们具有复制运动健康益处的独特能力。本综述重点关注几个关键概念,包括慢性炎症及其在慢性疾病中的作用、定期运动的抗炎作用以及绿茶中对健康有益的生物活性成分。它详细阐述了支持绿茶生物活性成分(例如表没食子儿茶素没食子酸酯 (EGCG))具有抗炎特性的科学证据,并理论化了这些生物活性成分如何在分子水平上复制运动的效果。通过对当前研究的全面分析,这篇综述提出了一个新的视角,即绿茶作为抑制慢性炎症的潜在干预策略的应用,从而扩大与运动所带来的益处类似。
更新日期:2024-05-03
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