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PROTAC-ing tuberculosis
Nature Chemical Biology ( IF 12.9 ) Pub Date : 2024-05-23 , DOI: 10.1038/s41589-024-01624-2
Delia Preti 1 , Valentina Albanese 2 , Peggy Carla Raffaella Marconi 1
Affiliation  

Targeted protein degradation has emerged as a promising approach in drug discovery, harnessing a cell’s intrinsic machinery to eliminate disease-related proteins. Now, a study paves the way to translating this technology into potential anti-mycobacterial therapies, by exploiting the bacterial protein-degradation complex.

中文翻译:

 结核病


靶向蛋白质降解已成为药物发现中一种有前途的方法,利用细胞的内在机制来消除与疾病相关的蛋白质。现在,一项研究通过利用细菌蛋白质降解复合物,为将该技术转化为潜在的抗分枝杆菌疗法铺平了道路。
更新日期:2024-05-23
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