DALT: the brain’s border patrol,Cell Research

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DALT: the brain’s border patrol
Cell Research ( IF 28.1 ) Pub Date : 2024-05-22 , DOI: 10.1038/s41422-024-00976-7
Jang Hyun Park _{1,

2} , Jenolyn F Alexander _{1,

2} , Leon C D Smyth _{1,

2} , Jonathan Kipnis _{1,

2}

Affiliation

Mucosal-associated lymphoid tissues are the immune structures that rapidly initiate local immune responses; the dura mater is the outermost layer of the meninges covering and connecting central nervous system (CNS) with the periphery. In a recent work published in Nature, Fitzpatrick et al. demonstrate the presence of dura-associated lymphoid tissue, which forms during early postnatal development and expands following infections to protect the fenestrated dural vasculature and prevent pathogen entry into the CNS.

中文翻译：

DALT：大脑的边境巡逻

粘膜相关淋巴组织是快速启动局部免疫反应的免疫结构；硬脑膜是脑膜的最外层，覆盖并连接中枢神经系统（CNS）与周围。 Fitzpatrick 等人最近在《自然》杂志上发表了一篇论文。证明了硬脑膜相关淋巴组织的存在，该组织在出生后早期发育过程中形成，并在感染后扩张，以保护有窗的硬脑膜脉管系统并防止病原体进入中枢神经系统。

更新日期：2024-05-22

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