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A key to unlock ubiquitin ligase function
Nature Chemical Biology ( IF 12.9 ) Pub Date : 2024-05-21 , DOI: 10.1038/s41589-024-01591-8
Shaoshuai Xie 1 , Gang Li 1
Affiliation  

Reliably identifying ubiquitin ligase interactors and substrates has been a persistent challenge in cellular biology. A breakthrough comes in the form of a potent, selective and cell-active chemical probe, shedding light on the intricate functions of a key regulatory enzyme.

中文翻译:


解锁泛素连接酶功能的钥匙



可靠地识别泛素连接酶相互作用物和底物一直是细胞生物学中的一个持续挑战。一种有效的、选择性的、具有细胞活性的化学探针取得了突破,揭示了一种关键调节酶的复杂功能。
更新日期:2024-05-21
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