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Bile acid receptor protects against diabetic cardiomyopathy
Nature Reviews Cardiology ( IF 41.7 ) Pub Date : 2024-05-20 , DOI: 10.1038/s41569-024-01040-y Irene Fernández-Ruiz 1
Nature Reviews Cardiology ( IF 41.7 ) Pub Date : 2024-05-20 , DOI: 10.1038/s41569-024-01040-y Irene Fernández-Ruiz 1
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Activation of the bile acid receptor TGR5 inhibits CD36-mediated fatty acid uptake in cardiomyocytes and protects against cardiac lipotoxicity and the development of diabetic cardiomyopathy in mice, according to a new study.
中文翻译:
胆汁酸受体可预防糖尿病心肌病
一项新的研究表明,胆汁酸受体 TGR5 的激活可抑制心肌细胞中 CD36 介导的脂肪酸摄取,并防止小鼠心脏脂毒性和糖尿病性心肌病的发展。
更新日期:2024-05-20
中文翻译:
胆汁酸受体可预防糖尿病心肌病
一项新的研究表明,胆汁酸受体 TGR5 的激活可抑制心肌细胞中 CD36 介导的脂肪酸摄取,并防止小鼠心脏脂毒性和糖尿病性心肌病的发展。