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Advancing programmable gene expression in plants using CRISPRi-based Boolean gates
Nature Biotechnology ( IF 33.1 ) Pub Date : 2024-05-20 , DOI: 10.1038/s41587-024-02273-5


To advance the toolset for controlling plant gene expression, we developed a CRISPR interference-based platform for the construction of synthetic Boolean logic gates that is functional in multiple plant species. These genetic circuits are programmable and reversible in nature, which will enable spatiotemporal control of plant responses to dynamic cues.

中文翻译:


使用基于 CRISPRi 的布尔门推进植物中的可编程基因表达



为了改进控制植物基因表达的工具集,我们开发了一个基于 CRISPR 干扰的平台,用于构建可在多种植物物种中发挥作用的合成布尔逻辑门。这些遗传电路本质上是可编程和可逆的,这将使植物对动态线索的反应能够进行时空控制。
更新日期:2024-05-20
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