Hypertension is recognised as a leading attributable risk factor for cardiovascular disease and premature mortality. Global initiatives towards the prevention and treatment of arterial hypertension are centred around non-pharmacological lifestyle modification. Exercise recommendations differ between professional and scientific organisations, but are generally unanimous on the primary role of traditional aerobic and dynamic resistance exercise. In recent years, isometric exercise training (IET) has emerged as an effective novel exercise intervention with consistent evidence of reductions in blood pressure (BP) superior to that reported from traditional guideline-recommended exercise modes. Despite a wealth of emerging new data and endorsement by select governing bodies, IET remains underutilised and is not widely prescribed in clinical practice. This expert-informed review critically examines the role of IET as a potential adjuvant tool in the future clinical management of BP. We explore the efficacy, prescription protocols, evidence quality and certainty, acute cardiovascular stimulus, and physiological mechanisms underpinning its anti-hypertensive effects. We end the review with take-home suggestions regarding the direction of future IET research.

高血压被认为是心血管疾病和过早死亡的主要危险因素。预防和治疗动脉高血压的全球举措以非药物生活方式改变为中心。专业组织和科学组织之间的运动建议有所不同，但对于传统有氧运动和动态抗阻运动的主要作用通常是一致的。近年来，等长运动训练（IET）已成为一种有效的新型运动干预措施，一致的证据表明其降低血压（BP）的效果优于传统指南推荐的运动模式。尽管出现了大量新数据并得到了特定管理机构的认可，但 IET 仍未得到充分利用，并且在临床实践中并未广泛使用。这篇专家知情的综述严格审查了 IET 作为未来 BP 临床管理中潜在辅助工具的作用。我们探讨了其功效、处方方案、证据质量和确定性、急性心血管刺激以及支撑其抗高血压作用的生理机制。我们以关于未来 IET 研究方向的带回家的建议结束了审查。