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Design multifunctional Mg–Zr coatings regulating Mg alloy bioabsorption
Journal of Magnesium and Alloys ( IF 15.8 ) Pub Date : 2024-04-19 , DOI: 10.1016/j.jma.2024.04.009 Zohra Benzarti , Sandesh Itani , José David Castro , Sandra Carvalho , Ana Sofia Ramos
Journal of Magnesium and Alloys ( IF 15.8 ) Pub Date : 2024-04-19 , DOI: 10.1016/j.jma.2024.04.009 Zohra Benzarti , Sandesh Itani , José David Castro , Sandra Carvalho , Ana Sofia Ramos
Magnesium (Mg) alloys are widely used for temporary bone implants due to their favorable biodegradability, cytocompatibility, hemocompatibility, and close mechanical properties to bone. However, rapid degradation and inadequate strength limit their applicability. To overcome this, the direct current magnetron sputtering technique is employed for surface coating in Mg-based alloys using various zirconium (Zr) content. This approach presents a promising strategy for simultaneously improving corrosion resistance, maintaining biocompatibility, and enhancing strength without compromising osseointegration. By leveraging Mg's inherent biodegradability, it has the potential to minimize the need for secondary surgeries, thereby reducing costs and resources.
中文翻译:
设计调节镁合金生物吸收的多功能镁锆涂层
镁(Mg)合金因其良好的生物降解性、细胞相容性、血液相容性以及与骨接近的机械性能而被广泛用于临时骨植入物。然而,快速降解和强度不足限制了它们的应用。为了克服这个问题,采用直流磁控溅射技术对不同锆(Zr)含量的镁基合金进行表面涂层。这种方法提出了一种有前景的策略,可以在不影响骨整合的情况下同时提高耐腐蚀性、保持生物相容性和增强强度。通过利用镁固有的生物降解性,它有可能最大限度地减少二次手术的需要,从而降低成本和资源。
更新日期:2024-04-19
中文翻译:
设计调节镁合金生物吸收的多功能镁锆涂层
镁(Mg)合金因其良好的生物降解性、细胞相容性、血液相容性以及与骨接近的机械性能而被广泛用于临时骨植入物。然而,快速降解和强度不足限制了它们的应用。为了克服这个问题,采用直流磁控溅射技术对不同锆(Zr)含量的镁基合金进行表面涂层。这种方法提出了一种有前景的策略,可以在不影响骨整合的情况下同时提高耐腐蚀性、保持生物相容性和增强强度。通过利用镁固有的生物降解性,它有可能最大限度地减少二次手术的需要,从而降低成本和资源。