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Sodium citrate targeting Ca2+/CAMKK2 pathway exhibits anti-tumor activity through inducing apoptosis and ferroptosis in ovarian cancer
Journal of Advanced Research ( IF 11.4 ) Pub Date : 2024-05-07 , DOI: 10.1016/j.jare.2024.04.033 Yulun Wu 1 , Chaoran Jia 2 , Wei Liu 3 , Wei Zhan 4 , Yao Chen 2 , Junlin Lu 3 , Yongli Bao 1 , Shuyue Wang 3 , Chunlei Yu 3 , Lihua Zheng 1 , Luguo Sun 3 , Zhenbo Song 1
Journal of Advanced Research ( IF 11.4 ) Pub Date : 2024-05-07 , DOI: 10.1016/j.jare.2024.04.033 Yulun Wu 1 , Chaoran Jia 2 , Wei Liu 3 , Wei Zhan 4 , Yao Chen 2 , Junlin Lu 3 , Yongli Bao 1 , Shuyue Wang 3 , Chunlei Yu 3 , Lihua Zheng 1 , Luguo Sun 3 , Zhenbo Song 1
Affiliation
Ovarian cancer (OC) is known for its high mortality rate. Although sodium citrate has anti-tumor effects in various cancers, its effect and mechanism in OC remain unclear.
中文翻译:
靶向 Ca2+/CAMKK2 通路的柠檬酸钠通过诱导卵巢癌细胞凋亡和铁死亡表现出抗肿瘤活性
卵巢癌 (OC) 以其高死亡率而闻名。尽管柠檬酸钠在多种癌症中具有抗肿瘤作用,但其在 OC 中的作用和机制仍不清楚。
更新日期:2024-05-07
中文翻译:
靶向 Ca2+/CAMKK2 通路的柠檬酸钠通过诱导卵巢癌细胞凋亡和铁死亡表现出抗肿瘤活性
卵巢癌 (OC) 以其高死亡率而闻名。尽管柠檬酸钠在多种癌症中具有抗肿瘤作用,但其在 OC 中的作用和机制仍不清楚。