Background There is limited data regarding the morbidity and progression to primary angle closure glaucoma in those presenting with acute primary angle closure (APAC) in the UK. We aim to report on the vision and intraocular pressure (IOP) outcomes and treatment required after an APAC episode and to identify any risk factors that could predict worse outcomes. Methods A retrospective observational case series review including 117 consecutive patients (121 eyes) attending Moorfields Eye Hospital, at a tertiary referral unit in the UK, with APAC was performed. Results Most patients (73%) had visual acuities of ≥6/12, meeting the UK driving standard, at the final follow-up. Only 15% (17 eyes) had severe visual impairment, as defined by the WHO, in the affected eye, of which 6.6% (eight eyes) were due to glaucoma. The delayed presentation was linked to a higher need for further medical treatment (OR=2.83, 95% CI 1.09 to 7.40, p=0.03). Patients who underwent phacoemulsification were at lower risk of having blindness in the affected eye (OR 0.18, 95% CI 0.05 to 0.69, p=0.01), having elevated IOP (OR 0.10, 95% CI 0.01 to 0.75, p=0.02) or requiring further medical treatment (OR 0.34, 95% CI 0.12 to 0.99, p=0.04). Older age (OR 1.26, 95% CI 1.08 to 1.48, p<0.01) was associated with worse visual outcomes. Conclusions APAC causes low long-term visual and treatment morbidity in this largely Caucasian patient group in the UK. Phacoemulsification as a treatment may enhance visual outcomes and reduce the need for further IOP-lowering treatment. No data are available. Not applicable.

中文翻译：

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急性原发性房角闭合术后的长期结局：英国 Moorfields 眼科医院的病例系列


背景：关于英国急性原发性闭角型 （APAC） 患者的发病率和进展为原发性闭角型青光眼的数据有限。我们的目标是报告 APAC 发作后视力和眼压 （IOP） 结果和所需的治疗，并确定任何可以预测更差结果的风险因素。方法 进行回顾性观察性病例系列回顾，包括 117 例连续 （121 只眼） 在英国三级转诊单位的 Moorfields 眼科医院就诊的亚太地区患者。结果 大多数患者 （73%） 在最终随访时视力为 ≥6/12，符合英国驾驶标准。只有 15%（17 只眼睛）的患眼有严重的视力障碍，如 WHO 所定义，其中 6.6%（8 只眼睛）是由于青光眼造成的。延迟就诊与对进一步药物治疗的更高需求有关（OR=2.83,95% CI 1.09 至 7.40，p=0.03）。接受超声乳化术的患者患眼失明（OR 0.18,95% CI 0.05 至 0.69，p=0.01）、眼压升高（OR 0.10,95% CI 0.01 至 0.75，p=0.02）或需要进一步药物治疗（OR 0.34,95% CI 0.12 至 0.99，p=0.04）的风险较低。高龄 （OR 1.26,95% CI 1.08 至 1.48，p<0.01） 与较差的视力结局相关。结论 APAC 导致英国这个以白人为主的患者群体的长期视力和治疗发病率较低。超声乳化术作为一种治疗方法可能会增强视力结局并减少进一步降低眼压治疗的需求。没有可用的数据。不適用。