Wound infection is a worldwide health issue that not only brings large detrimental effects to people’s physical and mental health, but also causes substantial economic burdens to society. By using traditional surgical debridement and antibiotic therapy, patients generally suffer more pain and are at risk of recurring infections. Thus, the development of non-antibiotic treatment methods is desperately needed. Currently, the emerging of flexible wound dressings with physiological signal detection, inactivated infectious pathogen, and wound-healing promoting properties has exhibited immense potential for the treatment of infected wound. Among various dressings, MXene‐based flexible electronic materials as wound dressings with special electroactive, mechanical, photophysical, and biological performances possess a broad application prospect in healthcare. In this review, the challenges of infected wound management are introduced. Next, the types of MXene-based flexible materials and wound infection features are outlined. Then the recent advance of MXene-based flexible materials for infected wound detection and treatment is summarized. Lastly, the predicaments, prospects, and future directions of MXene-based flexible materials for infected wound management are discussed.

伤口感染是一个世界性的健康问题，不仅给人们的身心健康带来很大的不利影响，而且给社会造成巨大的经济负担。通过使用传统的手术清创和抗生素治疗，患者通常会遭受更多疼痛，并且面临反复感染的风险。因此，迫切需要开发非抗生素治疗方法。目前，具有生理信号检测、灭活传染性病原体和促进伤口愈合特性的柔性伤口敷料的出现，在治疗感染伤口方面展现出巨大的潜力。在各种敷料中，MXene基柔性电子材料作为伤口敷料，具有特殊的电活性、机械、光物理和生物性能，在医疗保健领域具有广阔的应用前景。在这篇综述中，介绍了感染伤口管理的挑战。接下来，概述了基于 MXene 的柔性材料的类型和伤口感染特征。然后总结了基于 MXene 的柔性材料用于感染伤口检测和治疗的最新进展。最后，讨论了基于 MXene 的柔性材料用于感染伤口处理的困境、前景和未来方向。