AimThis retrospective cohort study aimed to volumetrically investigate the bone stability rate of prefabricated allogeneic bone blocks (PBB) and computer‐aided design (CAD)/computer‐aided manufacturing (CAM) custom‐milled allogeneic bone blocks (CCBB) for ridge augmentation.Materials and MethodsNineteen patients were treated with 20 allografts: 11 CCBB, 9 PBB; 10 in the maxilla and 10 in the mandible. Clinical treatment history and cone beam computed tomography scans before surgery (t0), directly after graft surgery (t1) and after 6 months of healing prior to implant insertion (t2) were evaluated using a three‐dimensional evaluation software for absolute bone volume, stability as well as vertical and horizontal bone gain. Furthermore, the inserted implants were analysed for survival, marginal bone loss (MBL) and complications for a mean follow‐up period of 43.75 (±33.94) months.ResultsA mean absolute volume of 2228.1 mm3 (±1205) was grafted at t1. The bone stability rate was 87.6% (±9.9) for CCBB and 83.0% (±14.5) for PBB. The stability was higher in the maxilla (91.6%) than in the mandible (79.53%). Surgery time of PBB was longer than for CCBB (mean Δ = 52 min). The survival rate of the inserted implants was 100% with a mean MBL of 0.41 mm (±0.37).ConclusionThe clinical performance of both allograft block designs was equally satisfactory for vertical and horizontal bone grafting prior to implant placement.Clinical Trial RegistrationClinicalTrials.gov: NCT06027710.

中文翻译：

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CAD/CAM 定制铣削与预制同种异体块重塑 6 个月时的三维成像分析以及牙种植体的长期随访：一项回顾性队列研究


目的这项回顾性队列研究旨在从体积角度研究用于牙槽嵴增量的预制同种异体骨块 (PBB) 和计算机辅助设计 (CAD)/计算机辅助制造 (CAM) 定制铣削同种异体骨块 (CCBB) 的骨稳定性。 材料方法 19 名患者接受 20 个同种异体移植：11 个 CCBB，9 个 PBB；上颌骨有 10 个，下颌骨有 10 个。临床治疗史和术前锥形束计算机断层扫描（ t 0 ），移植手术后立即（ t 1 ）以及种植体植入前愈合 6 个月后（ t 2 ）使用三维评估软件对绝对骨量、稳定性以及垂直和水平骨增量进行评估。此外，在平均 43.75 (±33.94) 个月的随访期内对插入的种植体的存活率、边缘骨丢失 (MBL) 和并发症进行了分析。结果平均绝对体积为 2228.1 mm 3 (±1205) 嫁接于t 1 。 CCBB 的骨稳定性率为 87.6%（±9.9），PBB 的骨稳定性率为 83.0%（±14.5）。上颌骨的稳定性（91.6%）高于下颌骨的稳定性（79.53%）。 PBB 的手术时间比 CCBB 长（平均 Δ = 52 分钟）。植入种植体的存活率为 100%，平均 MBL 为 0.41 mm (±0.37)。结论 对于种植体植入前的垂直和水平骨移植，两种同种异体骨块设计的临床表现同样令人满意。临床试验注册临床试验网：NCT06027710。