Base-promoted fused β-carboline formation from 2-(1H-indol-3-yl)cyclohexan-1-ones, aldehydes and ammonium salts,Organic Chemistry Frontiers

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Base-promoted fused β-carboline formation from 2-(1H-indol-3-yl)cyclohexan-1-ones, aldehydes and ammonium salts
Organic Chemistry Frontiers ( IF 4.6 ) Pub Date : 2024-05-08 , DOI: 10.1039/d4qo00551a
Jinjin Chen _{1,

2} , Yu Zhang ₁ , Xinping Liu ₁ , Kang Liu ₁ , Junting Wu ₁ , Xinlei Peng ₁ , Guo-Jun Deng ₂

Affiliation

A novel base-promoted fused β-carboline formation strategy from 2-(1H-indol-3-yl)cyclohexan-1-ones, aldehydes and ammonium salts has been developed. In this cascade reaction, ammonium salts served as a convenient nitrogen source and simultaneously played an important role in selectivity control, which can efficiently afford two different types of β-carbolines in satisfactory yields.

中文翻译：

碱促进 2-(1H-吲哚-3-基)环己烷-1-酮、醛和铵盐形成稠合 β-咔啉

开发了一种由 2-(1 H-吲哚-3-基)环己烷-1-酮、醛和铵盐形成的新型碱促进稠合 β-咔啉形成策略。在该级联反应中，铵盐作为一种方便的氮源，同时在选择性控制中发挥了重要作用，可以有效地以令人满意的产率提供两种不同类型的β-咔啉。

更新日期：2024-05-08

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